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Named reactions

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Protecting Groups

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Huisgen Cycloaddition

Huisgen Cycloaddition

Mechanism of the Huisgen Cycloaddition

Reference

Original reference Angew. Chem. Int. Ed. 1963, 2, 565.
Wikipedia link
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Sample reactions

This reaction is from the synthesis of Aflatoxin B2 by Elias J. Corey. Show me the full synthesis.

Reactant structure + Reactant structure
Reagent structure
Reaction arrow head
MeCN
RT, 5 h
65%
Product structure

This reaction is from the synthesis of Martinellic Acid by Barry B. Snider. Show me the full synthesis.

Reactant structure
N-Benzylglycine
Dean-Stark
Reaction arrow head
PhMe
Reflux, 15 h
57%
Product structure

This reaction is from the synthesis of Luciduline by Wolfgang Oppolzer. Show me the full synthesis.

Reactant structure
(CH2O)n
Sealed tube
Reaction arrow head
PhMe
115 °C, 14 h
70%
Product structure

This reaction is from the synthesis of Nominine by David Y. Gin. Show me the full synthesis.

Reactant structure
Sealed tube
Reaction arrow head
THF
180 °C, 16 h
20%
Product structure

This reaction is from the synthesis of Hirsutene by Raymond L. Funk. Show me the full synthesis.

Reactant structure
MeNHOH.HCl, NaOEt
Reaction arrow head
PhMe, EtOH
Reflux, 24-36 h
75%
Product structure

This reaction is from the synthesis of Cocaine by Joseph J. Tufariello. Show me the full synthesis.

Reactant structure + Reactant structure
HgO
Reaction arrow head
PhMe
Reflux, 15 h
96%
Product structure

This reaction is from the synthesis of Cocaine by Joseph J. Tufariello. Show me the full synthesis.

Reactant structure
Reaction arrow head
Xylene(s)
Reflux, 3 h
Product structure
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