Synarchive logo

Named reactions

Get references and more from over 200 named organic chemical reaction

Go to the named reaction index

Protecting Groups

Get the conditions needed to install/remove a wide range of protecting groups.

Go to the protecting groups index

Search synthesis
Advanced Search - Browse all synthesis

Hofmann-Löffler-Freytag Reaction

Hofmann-Löffler-Freytag Reaction

Mechanism of the Hofmann-Löffler-Freytag Reaction

Mechanism of the Hofmann-Löffler-Freytag Reaction
Report an error

References

Original reference Ber. Dtsch. Chem. Ges. 1883, 16, 558.Ber. Dtsch. Chem. Ges. 1909, 42, 3427.
Wikipedia link


Sample reactions

This step is from the synthesis of Quinine by Paul Rabe. Show me the full synthesis.

Reactant structure
NaOEt
Reaction arrow head
EtOH
Reflux, 10 min
88 %
Product structure

This step is from the synthesis of Quinine by Milan Uskokovic. Show me the full synthesis.

Reactant structure
hν
Reaction arrow head
CF3CO2H
0 °C, 50 min
Product structure
homepage - authors - molecules - named reactions - protecting groups - advanced search - contact - advertising
© 2011-2013 SynArchive