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Named reactions

Get references and more from over 229 named organic chemical reaction

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Protecting Groups

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Search synthesis

Fischer Esterification

Fischer Esterification

Mechanism of the Fischer Esterification

Reference

Original reference Ber. Dtsch. Chem. Ges. 1895, 28, 3252.
Wikipedia link
Organic chemistry portal link


Sample reactions

This reaction is from the synthesis of Quinine by Robert B. Woodward. Show me the full synthesis.

Reactant structure
HCl
Reaction arrow head
EtOH
Reflux
Product structure

This reaction is from the synthesis of Quinine by Milan Uskokovic. Show me the full synthesis.

Reactant structure
BF3.OEt2
Reaction arrow head
AcOH
50 °C, 18 h
96%
Product structure

This reaction is from the synthesis of Suaveoline by James M. Cook. Show me the full synthesis.

Reactant structure
HCl
Reaction arrow head
MeOH
Reflux
Product structure

This reaction is from the synthesis of Suaveoline by James M. Cook. Show me the full synthesis.

Reactant structure
HCl
Reaction arrow head
MeOH
Reflux
88% (2 steps)
Product structure

This reaction is from the synthesis of Ammosamide B by William Fenical. Show me the full synthesis.

Reactant structure
H2SO4
Reaction arrow head
MeOH
60 °C, 60 min
Product structure

This reaction is from the synthesis of Pactamycin by Stephen Hanessian. Show me the full synthesis.

Reactant structure
BnOH, TsOH
Reaction arrow head
PhH
Reflux, 24 h
67%
Product structure

This reaction is from the synthesis of Oseltamivir by Barry M. Trost. Show me the full synthesis.

Reactant structure
TsOH
Reaction arrow head
EtOH
Reflux, 10 h
84% (2 steps)
Product structure

This reaction is from the synthesis of Cubane by John Tsanaktsidis. Show me the full synthesis.

Reactant structure
Dowex 50WX8 ®
Reaction arrow head
MeOH
Reflux, 24 h
47% (3 steps)
Product structure

This reaction is from the synthesis of Streptonigrone by Dale L. Boger. Show me the full synthesis.

Reactant structure
HCl
Reaction arrow head
MeOH
RT, 5 h
85%
Product structure

This reaction is from the synthesis of Methoxatin by Steven M. Weinreb. Show me the full synthesis.

Reactant structure
H2SO4
Reaction arrow head
MeOH
Reflux
50% (2 steps)
Product structure

This reaction is from the synthesis of 6-Demethyl-6-deoxytetracycline by Robert B. Woodward. Show me the full synthesis.

Reactant structure
H2SO4
Reaction arrow head
MeOH, CHCl3
Reflux, 24 h
44% (2 steps)
Product structure

This reaction is from the synthesis of 6-Demethyl-6-deoxytetracycline by Robert B. Woodward. Show me the full synthesis.

Reactant structure
H2SO4
Reaction arrow head
MeOH, CHCl3
Reflux, 24 h
69% (2 steps)
Product structure

This reaction is from the synthesis of 6-Demethyl-6-deoxytetracycline by Robert B. Woodward. Show me the full synthesis.

Reactant structure
H2SO4
Reaction arrow head
MeOH, CHCl3
Reflux, 20 h
66%
Product structure

This reaction is from the synthesis of 6-Demethyl-6-deoxytetracycline by Robert B. Woodward. Show me the full synthesis.

Reactant structure
TsOH
Dean-Stark
Reaction arrow head
PhMe
Reflux, 3 h
90%
Product structure

This reaction is from the synthesis of Cephalosporin C1 by Robert B. Woodward. Show me the full synthesis.

Reactant structure
Cl3CCH2OH, TsOH
Reaction arrow head
PhMe
Reflux
Product structure
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