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Named reactions

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Evans Asymmetric Aldol Addition

Evans Asymmetric Aldol Addition

Mechanism of the Evans Asymmetric Aldol Addition

References



Sample reactions

This reaction is from the synthesis of Zaragozic Acid C by David A. Evans. Show me the full synthesis.

Reactant structure + Reactant structure
n-Bu2BOTf, Et3N
Reaction arrow head
CH2Cl2
-78 to -40 °C, 2.5 h
96%
Product structure

This reaction is from the synthesis of Melithiazole C by Janine Cossy. Show me the full synthesis.

Reactant structure
n-Bu2BOTf, i-Pr2NEt, Acrolein
Reaction arrow head
CH2Cl2
-78 to 0 °C, 90 min
93%
Product structure

This reaction is from the synthesis of Elailoide by David A. Evans. Show me the full synthesis.

Reactant structure + Reactant structure
n-Bu2BOTf, Et3N
Reaction arrow head
CH2Cl2
-78 to 0 °C, 80 min
86%
Product structure

This reaction is from the synthesis of Okilactomycin by Amos B. Smith, III. Show me the full synthesis.

Reactant structure + Reactant structure
n-Bu2BOTf, Et3N
Reaction arrow head
CH2Cl2
-78 to 0 °C, 3.5 h
93%
Product structure
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