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Named reactions

Get references and more from over 229 named organic chemical reaction

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Protecting Groups

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Claisen Rearrangement

Claisen Rearrangement

Mechanism of the Claisen Rearrangement

Reference

Original reference Chem. Ber. 1912, 45, 3157.
Wikipedia link
Organic chemistry portal link


Sample reactions

This reaction is from the synthesis of Quinine by Yuichi Kobayashi. Show me the full synthesis.

Reactant structure
VinylOEt, Hg(OAc)2
Reaction arrow head
190 °C
Product structure

This reaction is from the synthesis of Ingenol by Isao Kuwajima. Show me the full synthesis.

Reactant structure
Cl2CHCO2H
Reaction arrow head
DMF
125 °C to Reflux, 90 min
79% (2 steps)
Product structure

This reaction is from the synthesis of Gymnomitrol by Steven C. Welch. Show me the full synthesis.

Reactant structure
HCl
Reaction arrow head
H2O
74% (2 steps)
Product structure

This reaction is from the synthesis of Quadrone by Steven D. Burke. Show me the full synthesis.

Reactant structure
Sealed tube
Reaction arrow head
187 to 200 °C, 6 h
94% (2 steps)
Product structure

This reaction is from the synthesis of Quadrone by Steven D. Burke. Show me the full synthesis.

Reactant structure
VinylOEt, Hg(OAc)2
Sealed tube
Reaction arrow head
Xylene(s)
250 °C
90%
Product structure

This reaction is from the synthesis of Azadirachtin by Steven V. Ley. Show me the full synthesis.

Reactant structure
μW
Reaction arrow head
1,2-Dichlorobenzene
185 °C, 20 min
86% (α), 83 % (β)
Product structure

This reaction is from the synthesis of Glycyrol by Hak Sung Kim. Show me the full synthesis.

Reactant structure
Reaction arrow head
PhNEt2
Reflux, 60 min
64%
Product structure

This reaction is from the synthesis of Echitamidine by Joan Bosch. Show me the full synthesis.

Reactant structure
Sealed tube
Reaction arrow head
PhMe
180-190 °C, 12 h
80%
Product structure

This reaction is from the synthesis of Marinopyrrole B by Derrick L. J. Clive. Show me the full synthesis.

Reactant structure
Reaction arrow head
PhMe
Reflux, 16 h
Product structure
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