Claisen Condensation

This step is from the synthesis of Quinine by Robert B. Woodward. Show me the full synthesis.

NaOEt

82 °C, 14 h
63 %

This step is from the synthesis of Strychnine by Larry E. Overman. Show me the full synthesis.

i-Pr₂NLi, MeO₂CCN

THF
-78 °C

This step is from the synthesis of Pentacycloanammoxic Acid by Elias J. Corey. Show me the full synthesis.

HCO₂Et, NaOMe

PhH
RT, 12 h

This step is from the synthesis of Penitrem D by Amos B. Smith, III. Show me the full synthesis.

NaH, HCO₂Et

THF
0 °C to RT, 3 h

This step is from the synthesis of Cholesterol by Robert B. Woodward. Show me the full synthesis.

HCO₂Et, NaOMe

PhH
RT, 30 min
94 %

This step is from the synthesis of Cholesterol by Robert B. Woodward. Show me the full synthesis.

HCO₂Et, NaOMe

PhH
RT, ON

This step is from the synthesis of Melithiazole C by Janine Cossy. Show me the full synthesis.

CDI, i-Pr₂NLi, MeOAc

THF
-78 to 0 °C, 4 h
72 % (2 steps)

This step is from the synthesis of Dibromophakellstatin by Daniel Romo. Show me the full synthesis.

TMS₂NK, ClCO₂Bn

THF
-78 °C, 6 h
70 %

This step is from the synthesis of Ingenol by Jeffrey D. Winkler. Show me the full synthesis.

MeO₂CCN, i-Pr₂NLi

THF, HMPA
-78 °C, 90 min
89 %

This step is from the synthesis of Ingenol by Jeffrey D. Winkler. Show me the full synthesis.

i-Pr₂NLi

Et₂O
-78 °C, 2 h

This step is from the synthesis of Gymnomitrol by Robert M. Coates. Show me the full synthesis.

NaH, HCO₂Et

THF
RT, 14 h
83 %

This step is from the synthesis of Morphine by James D. White. Show me the full synthesis.

KH, HCO₂Me

THF
RT, 8 h

This step is from the synthesis of Epolactaene by Yujiro Hayashi. Show me the full synthesis.

n-BuLi, MeCN

THF
-88 to -78 °C, 60 min
93 %

This step is from the synthesis of Dodecahedrane by Horst Prinzbach. Show me the full synthesis.

HCO₂Me, NaH

THF, MeOH
RT to 40 °C, 20 h
100 %

This step is from the synthesis of Morphine by Johann Mulzer. Show me the full synthesis.

HCO₂Me, NaOMe

PhH
95 %

This step is from the synthesis of Strychnine by Masakatsu Shibasaki. Show me the full synthesis.

i-Pr₂NLi

THF
-78 °C, 19 h
72 %

This step is from the synthesis of Strychnine by Martin E. Kuehne. Show me the full synthesis.

TMS₂NLi

THF
Reflux, 30 min

This step is from the synthesis of Panacene by Ken S. Feldman. Show me the full synthesis.

NaH

PhH
81 % (2 steps)

This step is from the synthesis of Nupharamine by Jerzy T. Wróbel. Show me the full synthesis.

Na, HCO₂Et

Et₂O
100 %

This step is from the synthesis of Bikaverin by Derek H. R. Barton. Show me the full synthesis.

(CO₂Et)₂, NaOEt

PhH
RT, 4 h
40 %

This step is from the synthesis of Streptonigrone by Dale L. Boger. Show me the full synthesis.

i-Pr₂NLi, EtOAc

THF, Hexane(s)
-78 °C to RT, 55 min
71 %

This step is from the synthesis of Streptonigrone by Marco A. Ciufolini. Show me the full synthesis.

NaH, EtOAc

PhMe
110 °C, 15 h

This step is from the synthesis of Coccinelline by Robert V. Stevens. Show me the full synthesis.

NaH

DME
Reflux, 17 h