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Brook Rearrangement

Brook Rearrangement

Mechanism of the Brook Rearrangement


Original reference Acc. Chem. Res. 1974, 7, 77.
Wikipedia link
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Sample reactions

This reaction is from the synthesis of Strychnine by Christopher D. Vanderwal. Show me the full synthesis.

Reactant structure
TMS2NNa, CuBr.Me2S
Reaction arrow head
0 to 65 °C, 95 min
Product structure
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