Aldol Condensation

This step is from the synthesis of Alkaloid 251F by Jeffrey Aubé. Show me the full synthesis.

MeLi, CuI

THF
0 °C to RT, 45 min
60 %

This step is from the synthesis of Penitrem D by Amos B. Smith, III. Show me the full synthesis.

KOt-Bu

THF
Reflux, 6 h
75 %

This step is from the synthesis of Lysergic Acid by Robert B. Woodward. Show me the full synthesis.

NaOMe

MeOH

This step is from the synthesis of Cholesterol by Robert B. Woodward. Show me the full synthesis.

NaOH

MeOH, H₂O
Reflux, 2 h
58 % (2 steps)

This step is from the synthesis of Cholesterol by Robert B. Woodward. Show me the full synthesis.

Piperidine, AcOH
Dean-Stark

PhH
60 °C, 60 min
66 % (2 steps)

This step is from the synthesis of Cyanocobalamin by Robert B. Woodward. Show me the full synthesis.

Pyrrolidinium acetate

MeOH

This step is from the synthesis of Gymnomitrol by Steven C. Welch. Show me the full synthesis.

KOH

EtOH
Reflux
84 %

This step is from the synthesis of Morphine by James D. White. Show me the full synthesis.

NaOH

THF, H₂O
RT, 10 h
70 % (3 steps)

This step is from the synthesis of Buckminsterfullerene by Lawrence T. Scott. Show me the full synthesis.

TiCl₄

o-Dichlorobenzene
85 %

This step is from the synthesis of Quadrone by Eiichi Yoshii. Show me the full synthesis.

NaOt-Amyl

PhH
Reflux, 3.5 h
89 %

This step is from the synthesis of Retigeranic Acid by Leo A. Paquette. Show me the full synthesis.

NaH

PhMe
Reflux, 18.5 h
66 %

This step is from the synthesis of Retigeranic Acid by Elias J. Corey. Show me the full synthesis.

Al₂O₃
4 Å MS

CH₂Cl₂
RT, 2 h
70 %

This step is from the synthesis of Hirsutene by Takeshi Matsumoto. Show me the full synthesis.

KOt-Bu

t-BuOH
0 °C, 60 min

This step is from the synthesis of Hirsutene by Tarun K. Sarkar. Show me the full synthesis.

KOH

EtOH, H₂O
55 °C, 90 min
40 %

This step is from the synthesis of Hirsutene by Daniel D. Sternbach. Show me the full synthesis.

KOH, n-Bu₄N⁺ OH^-

THF, Et₂O
Reflux, ON
97 %

This step is from the synthesis of Methoxatin by Charles W. Rees. Show me the full synthesis.

NaOMe

MeOH, THF
-10 to 2 °C, 18 h
90 %

This step is from the synthesis of Corannulene by Jay S. Siegel. Show me the full synthesis.

KOH

MeOH
RT, 30 min
85 %

This step is from the synthesis of Bikaverin by Derek H. R. Barton. Show me the full synthesis.

MeCN, Me₃N⁺Bn HO^-
Dean-Stark

PhH
Reflux, 2 h
82 %