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Named reactions

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Aldol Condensation

Aldol Condensation

Mechanism of the Aldol Condensation

Reference

Original reference Bull. Soc. Chim. Fr. 1872, 17, 436.
http://gallica.bnf.fr/ark:/12148/bpt6k281966q.image.r=Bulletin+de+la+Société+chimique+de+France.f447.langFR
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Sample reactions

This reaction is from the synthesis of Alkaloid 251F by Jeffrey Aubé. Show me the full synthesis.

Reactant structure + Reactant structure
MeLi, CuI
Reaction arrow head
THF
0 °C to RT, 45 min
60 %
Product structure

This reaction is from the synthesis of Penitrem D by Amos B. Smith, III. Show me the full synthesis.

Reactant structure
KOt-Bu
Reaction arrow head
THF
Reflux, 6 h
75 %
Product structure

This reaction is from the synthesis of Lysergic Acid by Robert B. Woodward. Show me the full synthesis.

Reactant structure
NaOMe
Reaction arrow head
MeOH
Product structure

This reaction is from the synthesis of Cholesterol by Robert B. Woodward. Show me the full synthesis.

Reactant structure
NaOH
Reaction arrow head
MeOH, H2O
Reflux, 2 h
58 % (2 steps)
Product structure

This reaction is from the synthesis of Cholesterol by Robert B. Woodward. Show me the full synthesis.

Reactant structure
Piperidine, AcOH
Dean-Stark
Reaction arrow head
PhH
60 °C, 60 min
66 % (2 steps)
Product structure

This reaction is from the synthesis of Cyanocobalamin by Robert B. Woodward. Show me the full synthesis.

Reactant structure
Pyrrolidinium acetate
Reaction arrow head
MeOH
Product structure

This reaction is from the synthesis of Gymnomitrol by Steven C. Welch. Show me the full synthesis.

Reactant structure
KOH
Reaction arrow head
EtOH
Reflux
84 %
Product structure

This reaction is from the synthesis of Morphine by James D. White. Show me the full synthesis.

Reactant structure
NaOH
Reaction arrow head
THF, H2O
RT, 10 h
70 % (3 steps)
Product structure

This reaction is from the synthesis of Buckminsterfullerene by Lawrence T. Scott. Show me the full synthesis.

Reactant structure
TiCl4
Reaction arrow head
o-Dichlorobenzene
85 %
Product structure

This reaction is from the synthesis of Quadrone by Eiichi Yoshii. Show me the full synthesis.

Reactant structure
NaOt-Amyl
Reaction arrow head
PhH
Reflux, 3.5 h
89 %
Product structure

This reaction is from the synthesis of Retigeranic Acid by Leo A. Paquette. Show me the full synthesis.

Reactant structure
NaH
Reaction arrow head
PhMe
Reflux, 18.5 h
66 %
Product structure

This reaction is from the synthesis of Retigeranic Acid by Elias J. Corey. Show me the full synthesis.

Reactant structure
Al2O3
4 Å MS
Reaction arrow head
CH2Cl2
RT, 2 h
70 %
Product structure

This reaction is from the synthesis of Hirsutene by Takeshi Matsumoto. Show me the full synthesis.

Reactant structure
KOt-Bu
Reaction arrow head
t-BuOH
0 °C, 60 min
Product structure

This reaction is from the synthesis of Hirsutene by Tarun K. Sarkar. Show me the full synthesis.

Reactant structure
KOH
Reaction arrow head
EtOH, H2O
55 °C, 90 min
40 %
Product structure

This reaction is from the synthesis of Hirsutene by Daniel D. Sternbach. Show me the full synthesis.

Reactant structure
KOH, n-Bu4N+ OH-
Reaction arrow head
THF, Et2O
Reflux, ON
97 %
Product structure

This reaction is from the synthesis of Methoxatin by Charles W. Rees. Show me the full synthesis.

Reactant structure + Reactant structure
NaOMe
Reaction arrow head
MeOH, THF
-10 to 2 °C, 18 h
90 %
Product structure

This reaction is from the synthesis of Corannulene by Jay S. Siegel. Show me the full synthesis.

Reactant structure + Reactant structure
KOH
Reaction arrow head
MeOH
RT, 30 min
85 %
Product structure

This reaction is from the synthesis of Bikaverin by Derek H. R. Barton. Show me the full synthesis.

Reactant structure
MeCN, Me3N+Bn HO-
Dean-Stark
Reaction arrow head
PhH
Reflux, 2 h
82 %
Product structure

This reaction is from the synthesis of Capnellene by Leo A. Paquette. Show me the full synthesis.

Reactant structure
n-Bu4N+ OH-, KOH
Reaction arrow head
THF, Et2O, H2O
Reflux, 4 h
84 % (2 steps)
Product structure

This reaction is from the synthesis of Methoxatin by Steven M. Weinreb. Show me the full synthesis.

Reactant structure + Reactant structure
KOH
Reaction arrow head
H2O
95 °C, 6 h
Product structure
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